Fightdrome: Panama Rose is a fast-paced combat card game based off of the 2002 cyberpunk Altered Carbon novels by Richard K. Morgan.

This game places gamers at the heart of the infamous Panama Rose combat arena, with Panama Rose being the first in a planned series of Fightdromes. Players take on the role of competitors who fight it out to determine which of them is superior. Before starting a game, players agree how to be declared winner: by playing until one player is out of cards, or by being the first player to reach an agreed number of "fame" points. Each round is referred to as a bout, and playing for "fame" points involves a series of bouts.

Each player has their fighter's digital consciousness (known as a stack) placed in an engineered or augmented body (known as a sleeve) for each bout. Your card deck will be customized depending on which combination of stack and sleeve you are using. Competitors must then kick, punch, and grapple their way to the top, attempting to outwit their opponent, place killing blows, and become the champion of the Fightdrome.